Extraordinary Trench Digging
نویسندگان
چکیده
منابع مشابه
Extraordinary claims require extraordinary evidence.
At the beginning of 2003, the Journal of Health Economics published a paper of great importance in public policy by DiMasi, Hansen, and Grabowski (referred to hereafter as “DHG 2003”). The paper is based primarily on confidential, proprietary data supplied by pharmaceutical companies to the Tufts Center for the Study of Drug Development, a research center that receives significant unrestricted ...
متن کاملExtraordinary claims require extraordinary evidence
We thank Light and Warburton (2005) [hereafter LW] for providing a context for us to further discuss and clarify our studies on the cost of new drug development (DiMasi et al., 2003 [hereafter DHG]; DiMasi et al., 1991b [hereafter DHGL]; Hansen, 1979). We disagree, however, with their analyses, comparators, and conclusions. Although LW suggest, through the invocation of selected reported cost f...
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متن کاملReply: Extraordinary Claims Without Extraordinary Evidence
This interchange is the latest in an ongoing debate beginning with Newman et al.'s [1999a] recommendation, based on analysis of GPS and earthquake data, that Frankel et al.'s [1996] estimate of California-level seismic hazard for the NMSZ should be reduced. Most points at issue, except for those related to the costs and benefits of the proposed new IBC2000 building code, have already been argue...
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The magnitude of the increasing problem of resistance really takes all its meaning when appraised side-by-side with the paucity of new antimicrobials reaching the market (1). Several factors have contributed to making antimicrobial discovery less fashionable nowadays. The gigantic costs of bringing a new compound to market, from the identification of a promising target at the preclinical stages...
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ژورنال
عنوان ژورنال: Scientific American
سال: 1902
ISSN: 0036-8733
DOI: 10.1038/scientificamerican06211902-434